Regulation of the deficiencies along the proximal distal axis of the chick wing-bud: a quantitative analysis.
نویسنده
چکیده
The wing-bud shows zero regulation following removal of a whole slice of the proximal-distal axis from stage 22 or later. Prior to this it is possible that it may show some regulation. Some of the apparent regulation may be explained by the way in which the limb grows. The bud never shows perfect size regulation or morphallaxis. The proximal-distal axis of the bud between shoulder and wrist expands uniformly from stage 20.
منابع مشابه
‘Regeneration’ of wing bud stumps of chick embryos and reactivation of Msx-1 and Shh expression in response to FGF-4 and ridge signals
We examined systematically the ability of chick limb bud stumps to regenerate distal structures when fibroblast growth factor (FGF)-4 is applied. When amputations were made within 600 mu m of the tip and FGF-4 applied either posteriorly or both apically and posteriorly, outgrowth of stump tissues occurred and a virtually complete skeleton developed. 'Regeneration' of distal structures was corre...
متن کاملSpecification of cell fate along the proximal-distal axis in the developing chick limb bud.
Pattern formation along the proximal-distal (PD) axis in the developing limb bud serves as a good model for learning how cell fate and regionalization of domains, which are essential processes in morphogenesis during development, are specified by positional information. In the present study, detailed fate maps for the limb bud of the chick embryo were constructed in order to gain insights into ...
متن کاملRegional differences in the morphology and motility of mesodermal cells from the early wing-bud of normal and talpid3 mutant chick embryos.
A method of culturing has been employed to compare the properties of cells migrating from small mesodermal explants taken from different regions of normal and mutant limb-buds at different stages of development. An analysis by time-lapse cinematography of the morphology and mobility of cells migrating from explants defines a distal region within the limb-bud where these properties are distinct ...
متن کاملFate maps and the pattern of cell division: a calculation for the chick wing-bud.
Given the growth rate throughout an embryonic rudiment, one can calculate how its parts must shift as it gets bigger, and so plot fate maps showing their future positions. The calculation is done here for the chick wing-bud from stage 18 to 25, using published data for mitotic index and cell packing density, and new measurements of size and shape. Two main findings are: (1) the wing-bud in this...
متن کاملThe development of functional innervation in the chick wing-bud following truncations and deletions of the proximal-distal axis.
Selections of the proximal-distal axis were removed so as to produce wings lacking entire skeletal levels. The innervation of the resulting limb from the appropriate spinal nerves was tested by electrophysiological recording, gross dissection and serial sections. Ther nerves form repeatable and ordered patterns in the modified limbs which can be readily related to the normal pattern. In general...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of embryology and experimental morphology
دوره 41 شماره
صفحات -
تاریخ انتشار 1977